Characteristics of hospitalised COVID-19 patients during the first two pandemic waves, Gauteng
S. Afr. j. infect. dis. (Online)
;
37(1)2022. figures, tables
Artículo
en Inglés
| AIM
| ID: biblio-1396018
ABSTRACT
Background:
Gauteng province (GP) was one of the most affected provinces in the country during the first two pandemic waves in South Africa. We aimed to describe the characteristics of coronavirus disease 2019 (COVID-19) patients admitted in one of the largest quaternary hospitals in GP during the first two waves.Objectives:
Study objectives were to determine factors associated with hospital admission during the second wave and to describe factors associated with in-hospital COVID-19 mortality.Method:
Data from a national hospital-based surveillance system of COVID-19 hospitalisations were used. Multivariable logistic regression models were conducted to compare patients hospitalised during wave 1 and wave 2, and to determine factors associated with in-hospital mortality.Results:
The case fatality ratio was the highest (39.95%) during wave 2. Factors associated with hospitalisation included age groups 4059 years (adjusted odds ratio [aOR] 2.14, 95% confidence interval [CI] 1.084.27), 6079 years (aOR 2.49, 95% CI 1.235.02) and ≥ 80 years (aOR 3.39, 95% CI 1.358.49). Factors associated with inhospital mortality included age groups 6079 years (aOR 2.55, 95% CI 1.115.84) and ≥ 80 years (aOR 5.66, 95% CI 2.1215.08); male sex (aOR 1.56, 95% CI 1.221.99); presence of an underlying comorbidity (aOR 1.76, 95% CI 1.372.26), as well as being admitted during postwave 2 (aOR 2.42, 95% CI 1.334.42).Conclusion:
Compared to the recent omicron-driven pandemic waves characterised by lower admission rates and less disease severity among younger patients, COVID-19 in-hospital mortality during the earlier waves was associated with older age, being male and having an underlying comorbidity.
Texto completo:
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Índice:
AIM (África)
Asunto principal:
Admisión del Paciente
/
Sistema de Vigilancia Sanitaria
/
Pandemias
/
COVID-19
/
Pacientes Internos
Tipo de estudio:
Estudio observacional
/
Estudio pronóstico
Idioma:
Inglés
Revista:
S. Afr. j. infect. dis. (Online)
Año:
2022
Tipo del documento:
Artículo
Institución/País de afiliación:
Department of Public Health and Outbreak Response, National Institute of Communicable Diseases/ZA
/
Department of Virology, Faculty of Health Sciences, University of the Witwatersrand/ZA
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