Adherence to Immunosuppressive Medications in Kidney Transplant Patients at Three Centers in Khartoum State, Sudan: A Cross-sectional Hospital Study
Sudan j. med. sci
;
17(3): 313-329, 2022. tales, figures
Artículo
en Inglés
| AIM
| ID: biblio-1398201
ABSTRACT
Background:
Graft survival post-kidney transplantation is of paramount importance to patients and nephrologists. Nonadherence to immunosuppressive therapy can be associated with deterioration of renal function and graft rejection. This study aimed to evaluate the adherence to immunosuppressive medications in kidney transplant patients at three centers in Khartoum, Sudan.Methods:
In this descriptive cross-sectional hospital-based survey, 277 post-kidneytransplant patients were recruited. Data were collected using a questionnaire and analyzed using the SPSS v.23. Our scoring method was calculated based on Morisky Medication Adherence Scale (MMAS-8) related to immunosuppressive medications and was expressed as questions in the questionnaire; every correct answer was given one mark, then the marks were gathered and their summation was expressed.Results:
Overall, 33% ,45%, and 22% of the studied participants reported high, medium, and low adherence, respectively. The major factor for nonadherence was forgetfulness affecting 36.1% of those who did not adhere. The cost of the immunosuppressive medications did not negatively affect any of the participants' adherence (100%). However, a significant association was seen between adherence and occupational status, duration of transplantation, shortage of immunosuppressants, recognizing the name of immunosuppressant, side effect, and forgetfulness (P-values = 0.002, 0.01, 0.006 , 0.000, 0.022, and 0.000, respectively). Logistic regression analysis showed a significant association with occupational status, side effects, and forgetfulness.
Texto completo
- https://knepublishing.com/index.php/SJMS/article/view/12085/19500
- https://indexmedicus.afro.who.int/iah/fulltext/Adherence to Immunosuppressive Medications in Kidney Transplant Patients at Three Centers in Khartoum State, Sudan: A Cross-sectional Hospital Study.pdf
- https://fi-admin.bvsalud.org/document/view/6dmwn
Texto completo:
Disponible
Índice:
AIM (África)
Asunto principal:
Trasplante de Riñón
/
Cooperación del Paciente
Tipo de estudio:
Estudio de prevalencia
/
Factores de riesgo
Límite:
Humanos
País/Región como asunto:
Africa
Idioma:
Inglés
Revista:
Sudan j. med. sci
Año:
2022
Tipo del documento:
Artículo
Institución/País de afiliación:
2College of Medicine, Ajman University, Ajman, United Arab Emirates. Center of Medical and Bio-allied Health Sciences Research, Ajman University, Ajman/AE
/
Department of Clinical Pharmacy, Faculty of Pharmacy, Omdurman Islamic University/SD
/
Department of Clinical Pharmacy, Faculty of Pharmacy, Omdurman Islamic University, Khartoum/SD
/
Department of Medicine and HIV metabolic clinic, Milton Keynes University Hospital NHS Foundation Trust, Eagelstone, Milton Keynes/GB
Similares
MEDLINE
...
LILACS
LIS