Ferritin concentrations in low-birth babies in South-west Nigeria
Niger. j. paediatr
; 49(3): 261-265, 2022. tables
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| ID: biblio-1399083
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ABSTRACT
In the absence of acute phase reaction, ferritin concentration has been used as a standard measurement of iron stores. Low birth weight babies are at risk of developing iron lack because ferritin concentration at birth is influenced by duration of gestation, maternal iron status and conditions altering maternalfoetal iron exchange. Aim:
The aim of this study was to determine the ferritin concentrations of low birth weight babies in comparison with that of normal birth weight babies. Materials andmethods:
Fortyfour normal birth weight (NBW) babies and 40 low birth weight (LBW) babies were recruited for the study. About 1.0ml of venous blood was drawn aseptically from each subject into a micro EDTA tube, centrifuged at 5000rpm for 5 minutes, the plasma separated into cryotubes and stored at-20oC until ready for quantitative determination of ferritin concentrations using direct immunoenzymatic colorimetric method.Data obtained was analysed statistically using the Statistical Package for Social Sciences (SPSS,version 23, Chicago, IL, USA).Results:
Gestational age correlated positively with ferritin concentrations in LBW neonates (p<0.05)while APGAR score correlatepositively with ferritin concentrations in normal birth weight babies (r=0.398; p<0.05). Thoug not statistically significant (p=0.214), median values for ferritin concentrations were 188.5µg/ dl and 373µg/dl for LBW and NBW neonates respectively.Conclusion:
Gestational age correlated positively with ferritin concentrations in LBW neonatesPalabras clave
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Índice:
AIM
Asunto principal:
Puntaje de Apgar
/
Apoferritinas
Límite:
Humans
Idioma:
En
Revista:
Niger. j. paediatr
Año:
2022
Tipo del documento:
Article