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Indices in dental image exams for bone mineral density evaluation of aromatase inhibitor users
Barra, Sâmila Gonçalves; Arruda, José Alcides Almeida de; Souza, Alessandra Figueiredo; Brasileiro, Cláudia Borges; Camargos, Bruno Muzzi; Lima, Enaldo Melo de; Souza, Leandro Napier; Oliveira, Marina Chaves de; Macari, Soraia; Silva, Tarcília Aparecida; Abreu, Lucas Guimaraes; Mesquita, Ricardo Alves.
  • Barra, Sâmila Gonçalves; Universidade Federal de Minas Gerais. School of Dentistry. Department of Oral Surgery, Pathology and Clinical Dentistry. Belo Horizonte. BR
  • Arruda, José Alcides Almeida de; Universidade Federal de Minas Gerais. School of Dentistry. Department of Oral Surgery, Pathology and Clinical Dentistry. Belo Horizonte. BR
  • Souza, Alessandra Figueiredo; Universidade Federal de Minas Gerais. School of Dentistry. Department of Oral Surgery, Pathology and Clinical Dentistry. Belo Horizonte. BR
  • Brasileiro, Cláudia Borges; Universidade Federal de Minas Gerais. School of Dentistry. Department of Oral Surgery, Pathology and Clinical Dentistry. Belo Horizonte. BR
  • Camargos, Bruno Muzzi; Hospital Mater Dei. Bone Densitometry Center. Belo Horizonte. BR
  • Lima, Enaldo Melo de; Hospital Mater Dei. Bone Densitometry Center. Belo Horizonte. BR
  • Souza, Leandro Napier; Universidade Federal de Minas Gerais. School of Dentistry. Department of Oral Surgery, Pathology and Clinical Dentistry. Belo Horizonte. BR
  • Oliveira, Marina Chaves de; Universidade Federal de Minas Gerais. Nursing School. Department of Nutrition. Belo Horizonte. BR
  • Macari, Soraia; Universidade Federal de Minas Gerais. School of Dentistry. Department of Restorative Dentistry. Belo Horizonte. BR
  • Silva, Tarcília Aparecida; Universidade Federal de Minas Gerais. School of Dentistry. Department of Oral Surgery, Pathology and Clinical Dentistry. Belo Horizonte. BR
  • Abreu, Lucas Guimaraes; Universidade Federal de Minas Gerais. School of Dentistry. Department of Childs and Adolescents Oral Health. Belo Horizonte. BR
  • Mesquita, Ricardo Alves; Universidade Federal de Minas Gerais. School of Dentistry. Department of Oral Surgery, Pathology and Clinical Dentistry. Belo Horizonte. BR
Braz. oral res. (Online) ; 36: e138, 2022. tab, graf
Artículo en Inglés | LILACS-Express | LILACS, BBO | ID: biblio-1403960
ABSTRACT
Abstract We evaluated the accuracy of radiomorphometric indices (RI) and fractal dimension (FD) for screening bone mineral density (BMD) in postmenopausal patients who had breast cancer and were using aromatase inhibitors (AI). The sample consisted of 40 participants. Digital panoramic radiography (DPR) and cone beam computed tomography (CBCT) were evaluated along with dual-energy X-ray absorptiometry (DXA), which is the gold standard for detecting low BMD. According to the T-scores of DXA, the subjects were assigned into two groups with normal BMD and with low BMD (osteopenia and osteoporosis). The area under the curve (AUC), sensitivity, and specificity with their respective confidence intervals were determined for DPR and CBCT. For DPR indices, AUC ranged from 52.6 to 75.8%. The mandibular cortical width (MCW) had the highest AUC. For FD, the total trabecular index had the highest sensitivity, while the index anterior to the mental foramen (MF) had the highest specificity. In CBCT, the AUC ranged from 51.8 to 62.0%. The indices with the highest AUC were the molar (M) and anterior (A). The symphysis (S) index had the highest sensitivity and the posterior (P) index had the highest specificity. Sensitivity and specificity were adequate for the computed tomography index (Inferior; CTI [I]). Therefore, MCW, FD of the mandible angle, and total trabecular ROI in DPR and the CTI (I), M, P, and A indices in CBCT proved to be promising tools in distinguishing individuals with low BMD. Cutoff point for these indices could be a useful tool to investigate low BMD in postmenopausal women taking AI.


Texto completo: Disponible Índice: LILACS (Américas) Tipo de estudio: Estudio pronóstico Idioma: Inglés Revista: Braz. oral res. (Online) Asunto de la revista: Odontología Año: 2022 Tipo del documento: Artículo / Documento de proyecto País de afiliación: Brasil Institución/País de afiliación: Hospital Mater Dei/BR / Universidade Federal de Minas Gerais/BR

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Texto completo: Disponible Índice: LILACS (Américas) Tipo de estudio: Estudio pronóstico Idioma: Inglés Revista: Braz. oral res. (Online) Asunto de la revista: Odontología Año: 2022 Tipo del documento: Artículo / Documento de proyecto País de afiliación: Brasil Institución/País de afiliación: Hospital Mater Dei/BR / Universidade Federal de Minas Gerais/BR