Características y desenlace clínico de 30 pacientes con hemopatías malignas y COVID-19 en un hospital público regional / Features of COVID-19 infection among patients with hematological malignancies
Rev. méd. Chile
;
150(5): 625-633, mayo 2022. tab, graf
Artículo
en Español
| LILACS
| ID: biblio-1409841
ABSTRACT
BACKGROUND:
COVID-19 infection can be especially severe in certain risk populations such as patients with hematologic malignancies.Aim:
To describe the characteristics and clinical outcomes of a population of patients with hematologic malignancies and COVID-19. MATERIAL ANDMETHODS:
Review of medical records of patients with COVID-19 and hematologic malignancies, treated in Hematology Service of a regional hospital in Chile, between April 1 and October 30, 2020. Demographic characteristics, chronic comorbidities and clinical characteristics related to the underlying disease and COVID-19 infection were recorded.Results:
Thirty adults aged 17 to 73 years (67% men) with COVID-19 confirmed by RT-PCR, were evaluated. Forty percent had comorbidities, mainly hypertension (30%), obesity (27%) and diabetes (10%). Two thirds of cases came from a nosocomial outbreak and 77% were symptomatic. Half of the cases had mild disease and 20% required mechanical ventilation. Five patients (17%) died from COVID 19. Female sex, the presence of comorbidities and obesity were more common among deceased patients. Only 1 of 5 deceased patients were in complete remission. No differences were found in the mean survival according to requirement for intubation or the presence of complete remission.CONCLUSIONS:
This population with hematologic malignancies and COVID-19 had special characteristics leading to a greater fatality rate which, in this series, does not increase with the use of mechanical ventilation.
Texto completo:
Disponible
Índice:
LILACS (Américas)
Asunto principal:
Neoplasias Hematológicas
/
COVID-19
/
Hipertensión
Límite:
Adulto
/
Femenino
/
Humanos
/
Masculino
Idioma:
Español
Revista:
Rev. méd. Chile
Asunto de la revista:
Medicina
Año:
2022
Tipo del documento:
Artículo
País de afiliación:
Chile
Institución/País de afiliación:
Hospital Guillermo Grant Benavente/CL
/
Hospital Víctor Ríos Ruiz/CL
/
Universidad de Concepción/CL
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