Assessment of salivary opiorphin in oral lichen planus
Braz. j. oral sci
;
22: e237270, Jan.-Dec. 2023. ilus
Artículo
en Inglés
| LILACS, BBO
| ID: biblio-1413378
ABSTRACT
Opiorphin is a pentapeptide, which could be isolated from human fluids and has a decreasing effect on pain. Aim:
Since lichen planus is a chronic mucocutaneous disease, which causes pain or burning feeling in the oral mucosa, this study aimed to compare salivary opiorphin levels of oral lichen planus (OLP) patients with healthy subjects.Methods:
This case-control study, was performed on 24 patients with OLP lesions and 21 healthy subjects. After collecting unstimulated saliva, opiorphin levels were compared between two groups through statistical analyses.Results:
There was not any significant difference between OLP patients and healthy subjects according to salivary opiorphin concentration (p=0.378). Also, in the OLP group, opiorphin concentration was not significantly different between males and females (p=0.601). Analytical analysis could not show any remarkable difference between various severity of OLP lesions regarding to salivary opiorphin levels (p=0.653).Conclusion:
In this study, salivary opiorphin levels was not significantly different between patients with OLP and healthy subjects; however, more studies are suggested for better assessment of salivary opiorphin levels in various types of OLP lesions and its correlation with pain severityAsunto(s)
Texto completo:
Disponible
Índice:
LILACS (Américas)
Asunto principal:
Oligopéptidos
/
Dolor
/
Saliva
/
Liquen Plano Oral
Tipo de estudio:
Estudio observacional
Límite:
Adulto
/
Femenino
/
Humanos
/
Masculino
Idioma:
Inglés
Revista:
Braz. j. oral sci
Asunto de la revista:
Odontología
Año:
2023
Tipo del documento:
Artículo
País de afiliación:
Irán
Institución/País de afiliación:
Mashhad University of Medical Sciences/IR
Similares
MEDLINE
...
LILACS
LIS