Kidney Injury Biomarkers in Leptospirosis
Rev. Soc. Bras. Med. Trop
;
56: e0260, 2023. tab, graf
Artículo
en Inglés
|
LILACS-Express
| LILACS
| ID: biblio-1422906
ABSTRACT
ABSTRACT Leptospirosis is a zoonotic infection with a global distribution, though it has a greater impact on marginalized rural agricultural and urban communities in developing countries. Kidney injury, which can lead to severe and lethal infections, is the most frequent complication associated with leptospirosis. Novel biomarkers are being studied as tools for assessing kidney injury in different pathological processes to improve early detection. This review aimed to gather information on the use of novel kidney biomarkers for human leptospirosis. A search of the literature was carried out in September 2021 using the parameters "((kidney) OR (renal) OR (chronic kidney disease) OR (acute kidney injury)) AND ((biomarker) OR (marker)) AND ((Leptospira) OR (leptospirosis))". The review identified 11 original studies that evaluated the performance of 15 kidney biomarkers related to leptospirosis. Assessment of the evidence for biomarker utility was limited because of the small number of studies and sample sizes. Although some biomarkers were associated with kidney disease, no specific biomarker appeared to be ready for clinical practice, and more research in this field is necessary.
Texto completo:
Disponible
Índice:
LILACS (Américas)
Tipo de estudio:
Estudio de tamizaje
Idioma:
Inglés
Revista:
Rev. Soc. Bras. Med. Trop
Asunto de la revista:
Medicina Tropical
Año:
2023
Tipo del documento:
Artículo
/
Documento de proyecto
País de afiliación:
Colombia
/
Estados Unidos
Institución/País de afiliación:
Universidad CES/CO
/
University of Minnesota/US
Similares
MEDLINE
...
LILACS
LIS