Compounded drugs as an alternative to the therapeutical gaps of inborn errors of metabolism
Braz. J. Pharm. Sci. (Online)
;
59: e21109, 2023. tab, graf
Artículo
en Inglés
| LILACS
| ID: biblio-1429952
ABSTRACT
Abstract Inborn errors of metabolism are rare disorders with few therapeutic options for their treatments, which can make patients suffer with complications. Therefore, compounded drugs might be a promising option given that they have the ability of meeting the patient's specific needs, (i) identification of the main drugs described in the literature; (ii) proposal of compounding systems and (iii) calculation of the budgetary addition for the inclusion of these drugs into the Brazilian Unified Health System. The research conducted a literature review and used management data as well as data obtained from official Federal District government websites. The study identified 31 drugs for the treatment of inborn errors of metabolism. Fifty eight percent (58%) (18) of the medicines had their current demand identified, which are currently unmet by the local Health System. The estimated budget for the production of compounded drugs was of R$363,16.98 per year for approximately 300 patients. This estimated cost represents a budgetary addition of only 0.17% from the total of expenditures planned for drug acquirement. There is a therapeutic gap for inborn errors of metabolism and compounding pharmacies show potential in ensuring access to medicine therapy with a low-cost investment.
Texto completo:
Disponible
Índice:
LILACS (Américas)
Asunto principal:
Preparaciones Farmacéuticas
/
Metabolismo
/
Errores Innatos del Metabolismo
Tipo de estudio:
Evaluación Económica en Salud
Idioma:
Inglés
Revista:
Braz. J. Pharm. Sci. (Online)
Asunto de la revista:
Farmacologia
/
Teraputica
/
Toxicologia
Año:
2023
Tipo del documento:
Artículo
País de afiliación:
Brasil
Institución/País de afiliación:
State Department of Health of the Federal District/BR
/
University of Brasilia/BR
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