Genetic diversity of Mycobacterium leprae in the state of São Paulo, an area of low-leprosy incidence in Brazil
Rev. Soc. Bras. Med. Trop
;
56: e0612, 2023. graf
Artículo
en Inglés
|
LILACS-Express
| LILACS, SES-SP, SESSP-ILSLPROD, SES-SP, SESSP-ILSLACERVO, SES-SP
| ID: biblio-1431402
ABSTRACT
ABSTRACT Background:
Brazil has the second largest number of leprosy cases worldwide, and the state of São Paulo has been considered non-endemic since 2006.Methods:
We analyzed 16 variable number tandem repeats loci and three single nucleotide polymorphisms loci of Mycobacterium leprae (M. leprae) in 125 clinical isolates from patients in different municipalities in the state.Results:
The clustering pattern of M. leprae indicated that the transmission of leprosy persisted in the state and included scenarios of intra-extra-familial transmission in areas with low endemicity.Conclusions:
A significantly active circulation of M. leprae was observed. Therefore, surveillance and control measures must be implemented.
Texto completo:
Disponible
Índice:
LILACS (Américas)
Tipo de estudio:
Estudio de incidencia
/
Factores de riesgo
País/Región como asunto:
America del Sur
/
Brasil
Idioma:
Inglés
Revista:
Rev. Soc. Bras. Med. Trop
Año:
2023
Tipo del documento:
Artículo
Institución/País de afiliación:
Fundação Oswaldo Cruz/BR
/
Instituto Lauro de Souza Lima/BR
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