Maternal prepregnancy obesity and gestational diabetes influence on adverse perinatal outcomes
Arch. endocrinol. metab. (Online)
;
67(4): e000605, Mar.-Apr. 2023. tab, graf
Artículo
en Inglés
|
LILACS-Express
| LILACS
| ID: biblio-1439221
ABSTRACT
ABSTRACT Objective:
Evaluate the influence of isolated and associated prepregnancy obesity and gestational diabetes mellitus (GDM) on adverse perinatal outcomes. Materials andmethods:
Cross-sectional observational study with women who delivered at a Brazilian Maternity Hospital, between August and December 2020. Data were collected by interview with application form, and medical records. Sample was stratified by body mass index (BMI) and GDM screening in four groups no obesity (BMI < 30 kg/m2) no GDM - reference; isolated GDM; isolated obesity (BMI ≥ 30 kg/m2); and obesity with GDM. Preeclampsia (PE), cesarean section (CS), large-for-gestational-age (LGA) newborn and admission to neonatal intensive care unit (NICU) were analyzed by odds ratio (OR) adjusted for confounding factors, adopting 95% confidence interval (CI) and P < 0.05 statistically significant.Results:
From 1,618 participants, isolated obesity group (233/14.40%) had high chance of PE (OR = 2.16; CI 1.364-3.426; P = 0.001), isolated GDM group (190/11.74%) had high chance of CS (OR = 1.736; CI 1.136-2.652; P = 0.011) and NICU admission (OR = 2.32; CI 1.265-4.261; P = 0.007), and obesity with GDM group (121/7.48%) had high chance of PE (OR = 1.93; CI 1.074-3.484; P = 0.028), CS (OR = 1.925; CI 1.124-3.298; P = 0.017) and LGA newborn (OR = 1.81; CI 1.027-3.204; P = 0.040), compared with reference (1,074/66.38%).Conclusion:
Obesity and GDM enhances the chance of different negative outcomes, worsening this prognosis when associated.
Texto completo:
Disponible
Índice:
LILACS (Américas)
Tipo de estudio:
Estudio observacional
/
Estudio pronóstico
Idioma:
Inglés
Revista:
Arch. endocrinol. metab. (Online)
Asunto de la revista:
Endocrinologia
/
Metabolismo
Año:
2023
Tipo del documento:
Artículo
País de afiliación:
Brasil
Institución/País de afiliación:
Universidade da Região de Joinville/BR
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