Applicability of an HPLC method for analysis of alcoholic and glycolic Brazilian green-propolis extracts
Braz. J. Pharm. Sci. (Online)
;
59: e21972, 2023. tab, graf
Artículo
en Inglés
| LILACS
| ID: biblio-1439532
ABSTRACT
Abstract Brazilian green propolis has been widely used in food and pharmaceutical products due to its valuable source of phenolic compounds and versatile biological activities. The development and validation of analytical methods are extremely useful for the characterization and quality control of products containing propolis. Therefore, the aim of this study was to optimize, validate and investigate the applicability of a reversed-phase HPLC method for analysis of different types of Brazilian green propolis extracts (glycolic and ethanolic). The method showed to be selective for the propolis phenolic markers. The analysis of variance and residues demonstrated that the method had significant linear regression, without lack of fit. It was also a precise, accurate and robust method, which was of utmost importance to analyze both glycolic and ethanolic extracts and at different concentrations. Moreover, as these products can display most complex matrices to analyze, a valid HPLC method can also prove to be specific and versatile.
Texto completo:
Disponible
Índice:
LILACS (Américas)
Asunto principal:
Própolis
/
Cromatografía Líquida de Alta Presión
País/Región como asunto:
America del Sur
/
Brasil
Idioma:
Inglés
Revista:
Braz. J. Pharm. Sci. (Online)
Asunto de la revista:
Farmacologia
/
Teraputica
/
Toxicologia
Año:
2023
Tipo del documento:
Artículo
País de afiliación:
Brasil
Institución/País de afiliación:
State University of Maringa/BR
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