Stem cell therapy in stargardt disease: a systematic review
Journal of Ophthalmic and Vision Research
;
18(3): 318-327, 23/07/2023.
Artículo
en Inglés
| AIM
| ID: biblio-1443312
ABSTRACT
This article aimed to review current literature on the safety and efficacy of stem cell therapy in Stargardt disease. A comprehensive literature search was performed, and two animal and eleven human clinical trials were retrieved. These studies utilized different kinds of stem cells, including human or mouse embryonic stem cells, mesenchymal stem cells, bone marrow mononuclear fraction, and autologous bone marrow-derived stem cells. In addition, different injection techniques including subretinal, intravitreal, and suprachoroidal space injections have been evaluated. Although stem cell therapy holds promise in improving visual function in patients with Stargardt disease, further investigation is needed to determine the long-term benefits, safety, and efficacy in determining the best delivery method and selecting the most appropriate stem cell type.
Texto completo:
Disponible
Índice:
AIM (África)
Asunto principal:
Enfermedad de Stargardt
Tipo de estudio:
Revisiones Sistemáticas Evaluadas
Idioma:
Inglés
Revista:
Journal of Ophthalmic and Vision Research
Año:
2023
Tipo del documento:
Artículo
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