Long-term oncological and surgical outcomes after Video Endoscopic Inguinal Lymphadenectomy (VEIL) in patients with penile cancer
Int. braz. j. urol
;
49(5): 580-589, Sep.-Oct. 2023. tab, graf
Artículo
en Inglés
|
LILACS-Express
| LILACS
| ID: biblio-1506417
ABSTRACT
ABSTRACT Objective:
To report outcomes from the largest multicenter series of penile cancer patients undergoing video endoscopic inguinal lymphadenectomy (VEIL). Materials andMethods:
Retrospective multicenter analysis. Authors of 21 centers from the Penile Cancer Collaborative Coalition-Latin America (PeC-LA) were included. All centers performed the procedure following the same previously described standardized technique. Inclusion criteria included penile cancer patients with no palpable lymph nodes and intermediate/high-risk disease and those with non-fixed palpable lymph nodes less than 4 cm in diameter. Categorical variables are shown as percentages and frequencies whereas continuous variables as mean and range.Results:
From 2006 to 2020, 210 VEIL procedures were performed in 105 patients. Mean age was 58 (45-68) years old. Mean operative time was 90 minutes (60-120). Mean lymph node yield was 10 nodes (6-16). Complication rate was 15.7%, including severe complications in 1.9% of procedures. Lymphatic and skin complications were noted in 8.6 and 4.8% of patients, respectively. Histopathological analysis revealed lymph node involvement in 26.7% of patients with non-palpable nodes. Inguinal recurrence was observed in 2.8% of patients. 10y- overall survival was 74.2% and 10-y cancer specific survival was 84.8%. CSS for pN0, pN1, pN2 and pN3 were 100%, 82.4%, 72.7% and 9.1%, respectively.Conclusion:
VEIL seems to offer appropriate long term oncological control with minimal morbidity. In the absence of non-invasive stratification measures such as dynamic sentinel node biopsy, VEIL emerged as the alternative for the management of non-bulky lymph nodes in penile cancer.
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Índice:
LILACS (Américas)
Idioma:
Inglés
Revista:
Int. braz. j. urol
Asunto de la revista:
Urología
Año:
2023
Tipo del documento:
Artículo
País de afiliación:
Argentina
/
Brasil
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Ecuador
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México
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Perú
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Estados Unidos
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Uruguay
Institución/País de afiliación:
AC Camargo Cancer Center/BR
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Alexander Fleming Institute/AR
/
Centro Universitário Faculdade de Medicina do ABC/BR
/
Hospital Cancer de Londrina/BR
/
Hospital Carlos Andrade Marin/EC
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Hospital Câncer de Barretos/BR
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Hospital Felício Rocho/BR
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Hospital General de México Dr. Eduardo Liceaga/MX
/
Hospital Madre Teresa/BR
/
Hospital Pasteur/UY
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