Clinical and imaging research in the diagnosis of anorectal melanoma with surgical outcome: a case report and literature review
J. coloproctol. (Rio J., Impr.)
;
43(3): 221-223, July-sept. 2023. ilus
Artículo
en Inglés
| LILACS
| ID: biblio-1521145
ABSTRACT
Objective: This study aims to report the case of a 69-year-old female patient with a diagnosis of anorectal melanoma (AM) established by immunohistochemistry. Methods: Clinical case report, a descriptive and qualitative study. Results: The patient had a nodular and ulcerative lesion in the anal region, the imaging exams revealed an expansive lesion that affected the rectum and the vaginal wall. The chosen course of treatment was initial surgical intervention, the surgery and postoperative course progressed without complications, and the anatomopathological examination confirmed the diagnosis of invasive malignant melanoma of the distal rectum of anorectal transition. The anatomopathological examination confirmed the diagnosis of invasive malignant melanoma located in the distal rectum of the anorectal transition. Immunohistochemistry analysis showed infiltrative melanoma with microsatellites, as well as peri and intratumoral lymphocytic infiltrate, angiolymphatic invasion, and perineural invasion. The surgical resection margins, ovaries, posterior vaginal wall, and parametrium showed no signs of neoplastic involvement. Following the surgery, the patient began immunotherapy, which she is still undergoing. Conclusions: The survival rate of AM can be improved through various diagnostic and therapeutic modalities. However, further exploration of this topic through clinical studies is necessary to enhance both diagnosis and treatment. (AU)
Texto completo:
Disponible
Índice:
LILACS (Américas)
Asunto principal:
Neoplasias del Ano
/
Melanoma
Límite:
Anciano
/
Femenino
/
Humanos
Idioma:
Inglés
Revista:
J. coloproctol. (Rio J., Impr.)
Asunto de la revista:
Cirurgia
/
Doenas Retais
/
Doenas do Colo
/
Gastroenterologia
/
Cirurgia
Año:
2023
Tipo del documento:
Artículo
País de afiliación:
Brasil
Institución/País de afiliación:
Department of Medicine/BR
/
Pontifical Catholic University of Paraná/BR
/
Positiv University/BR
/
Santa Casa de Curitiba/BR
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