Clinical behavior of recurrent pleomorphic adenoma in the palate: a systematic review
Acta cir. bras
;
39: e390824, 2024. tab, graf, ilus
Artículo
en Inglés
| LILACS, VETINDEX
| ID: biblio-1533356
ABSTRACT
Purpose:
This systematic review analyzed the clinical behavior and odds of malignancy of the palatal recurrent pleomorphic adenomas.Methods:
Systematic review of patients with recurrent pleomorphic adenoma arising in the palate. Database search MEDLINE, Scopus, Web of Science, Cochrane, EMBASE, Virtual Health Library, Google Scholar, and OpenGrey. A binomial logistic regression was performed to assess the odds of detecting recurrence five, 10 and 20 years after the treatment of primary tumor.Results:
Thirteen studies (n = 18 patients) out of 336 were included. The recurrent pleomorphic adenoma in palate was more common in females (61.6%), average age was 49 years old (range 9-73 years old). Four patients progressed to malignant transformation. The odds ratio (OR) of detecting a recurrence at 10 (OR = 5.57; 95% confidence interval - 95%CI 1.13-27.52), and 20 years (OR = 18.78; 95%CI 3.18-110.84) after treatment of primary pleomorphic adenoma was significantly higher than at one-year follow-up.Conclusions:
The recurrence of pleomorphic adenoma in palate remains a rare event of late occurrence. It mainly affects middle-aged female and carries a risk of malignant transformation. Although uncommon, patients with palatal pleomorphic adenoma should be warned about the possibility of recurrence or malignant transformation of tumor at advanced ages.
Texto completo:
Disponible
Índice:
LILACS (Américas)
Asunto principal:
Hueso Paladar
/
Glándulas Salivales
/
Adenoma Pleomórfico
/
Neoplasias
Idioma:
Inglés
Revista:
Acta cir. bras
Asunto de la revista:
Cirugía General
/
Procedimentos Cir£rgicos Operat¢rios
Año:
2024
Tipo del documento:
Artículo
País de afiliación:
Brasil
/
Estados Unidos
Institución/País de afiliación:
Augusta University/US
/
Universidade de São Paulo/BR
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