A longitudinal study of the progression of Huntington's disease and oropharyngeal dysphagia: A four-case follow-up
Rev. CEFAC
;
26(2): e11123, 2024. tab, graf
Artículo
en Inglés
|
LILACS-Express
| LILACS
| ID: biblio-1558997
ABSTRACT
ABSTRACT Huntington's disease (HD) is a neurodegenerative disorder, with dysphagia being a common symptom of the disease. Few studies established a relationship between neuromotor impairment and dysphagia. There is also a lack of described therapeutic approaches for dysphagia in HD. This study aimed to better understand the progression of neurological clinical aspects, instrumental swallowing and dysphagia management in four patients presented with HD in an outpatient follow-up setting. The longitudinal follow-up period was 36 to 43 months through neuroclinical assessments (Unified Huntington's Disease Rating Scale) and fiberoptic endoscopic swallowing evaluations. Case 1 - a moderate decline of independence with safe swallowing. Case 2 - a moderate motor impairment, safe swallowing and moderate dysphagia during follow-up. Case 3 - a longer disease duration and increased motor impairment associated with moderate/severe dysphagia. Case 4 - a longer disease duration, need of assistance to perform daily activities, severe dysphagia and palliative care, considering the family decision of exclusive oral feeding. This longitudinal study revealed that the progression of neuromotor damage was not directly related to dysphagia development. This case series demonstrates the importance of follow-up settings with instrumental swallowing evaluations and careful consideration of early palliative care for HD patients.
Texto completo:
Disponible
Índice:
LILACS (Américas)
Idioma:
Inglés
Revista:
Rev. CEFAC
Asunto de la revista:
Terapia
/
Patología del Habla y Lenguaje
/
Terapia
/
ReabilitaÆo
Año:
2024
Tipo del documento:
Artículo
País de afiliación:
Brasil
Institución/País de afiliación:
Escola Superior de Ciências da Santa Casa de Misericórdia de Vitória/BR
/
Universidade Estadual de Campinas/BR
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