Glomerular loss after arteriovenous and arterial clamping for renal warm ischemia in a swine model
Acta cir. bras
;
31(11): 753-758, Nov. 2016. tab, graf
Artículo
en Inglés
| LILACS
| ID: biblio-827658
ABSTRACT
ABSTRACT PURPOSE:
To evaluate the glomerular loss after arteriovenous or arterial warm ischemia in a swine model.METHODS:
Twenty four pigs were divided into Group Sham (submitted to all surgical steps except the renal ischemia), Group AV (submitted to 30 minutes of warm ischemia by arteriovenous clamping of left kidney vessels), and Group A (submitted to 30 minutes of ischemia by arterial clamping). Right kidneys were used as controls. Weigh, volume, cortical volume, glomerular volumetric density (Vv[Glom]), volume-weighted glomerular volume (VWGV), and the total number of glomeruli were measured for each organ.RESULTS:
Group AV showed a 24.5% reduction in its left kidney Vv[Glom] and a 25.4% reduction in the VWGV, when compared to the right kidney. Reductions were also observed when compared to kidneys of sham group. There was a reduction of 19.2% in the total number of glomeruli in AV kidneys. No difference was observed in any parameters analyzed on the left kidneys from group A.CONCLUSIONS:
Renal warm ischemia of 30 minutes by arterial clamping did not caused significant glomerular damage, but arteriovenous clamping caused significant glomerular loss in a swine model. Clamping only the renal artery should be considered to minimize renal injury after partial nephrectomies.
Texto completo:
Disponible
Índice:
LILACS (Américas)
Asunto principal:
Arteria Renal
/
Laparoscopía
/
Isquemia Tibia
/
Glomérulos Renales
/
Nefrectomía
Límite:
Animales
Idioma:
Inglés
Revista:
Acta cir. bras
Asunto de la revista:
Cirugía General
/
Procedimentos Cir£rgicos Operat¢rios
Año:
2016
Tipo del documento:
Artículo
País de afiliación:
Brasil
Institución/País de afiliación:
Universidade Estadual do Rio de Janeiro/BR
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