Paradoxical psoriasis after the use of anti-TNF in a patient with rheumatoid arthritis
An. bras. dermatol
;
91(5,supl.1): 137-139, Sept.-Oct. 2016. graf
Artículo
en Inglés
| LILACS
| ID: biblio-837917
ABSTRACT
Abstract The use of tumor necrosis factor antagonists (anti-TNF) has become a usual practice to treat various inflammatory diseases. Although indicated for the treatment of psoriasis, anti-TNF may paradoxically trigger a psoriasiform condition. We present a case of a female patient who, during the use of infliximab for rheumatoid arthritis, developed psoriasis. In an attempt to switch anti-TNF class, we observed a cumulative worsening of the lesions requiring suspension of the immunobiological agent and the introduction of other drugs for clinical control. The therapeutic challenge of this paradoxical form of psoriasis is the focus of our discussion. The use of another anti-TNF in these patients is a matter of debate among experts.
Texto completo:
Disponible
Índice:
LILACS (Américas)
Asunto principal:
Artritis Reumatoide
/
Psoriasis
/
Factor de Necrosis Tumoral alfa
/
Antirreumáticos
/
Infliximab
Límite:
Adulto
/
Femenino
/
Humanos
Idioma:
Inglés
Revista:
An. bras. dermatol
Asunto de la revista:
Dermatologia
Año:
2016
Tipo del documento:
Artículo
País de afiliación:
Brasil
Institución/País de afiliación:
Universidade do Estado do Rio de Janeiro/BR
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