Angiosarcoma in HIV-negative patients is not associated with HHV-8
An. bras. dermatol
;
91(6): 738-741, Nov.-Dec. 2016. tab, graf
Artículo
en Inglés
| LILACS
| ID: biblio-837975
ABSTRACT
Abstract: BACKGROUND: Angiosarcoma is an aggressive, malignant neoplasm of vascular or lymphatic origin. Herpes virus 8 (HHV-8) is a member of the herpes family with a tropism for endothelial cells and it has been proven to induce vascular neoplasms, such as Kaposi's sarcoma. The role of HHV-8 in the pathogenesis of angiosarcoma has not been well defined. OBJECTIVE: To investigate the relationship between the presence of HHV-8 and angiosarcoma. METHODS: In this study, the team investigated the relationship between the presence of HHV-8, as determined by polymerase chain reaction, and angiosarcoma, using samples from patients with epidemic Kaposi's sarcoma as controls. RESULTS: While all control cases with epidemic Kaposi's sarcoma were positive for HHV-8, none of the angiosarcoma cases was. CONCLUSION: These findings support most previous studies that found no association between HHV-8 and angiosarcoma.
Texto completo:
Disponible
Índice:
LILACS (Américas)
Asunto principal:
Sarcoma de Kaposi
/
Neoplasias Cutáneas
/
Infecciones Oportunistas Relacionadas con el SIDA
/
Seronegatividad para VIH
/
Herpesvirus Humano 8
/
Hemangiosarcoma
Tipo de estudio:
Estudio observacional
/
Factores de riesgo
Límite:
Anciano
/
Aged80
/
Femenino
/
Humanos
/
Masculino
País/Región como asunto:
America del Sur
/
Brasil
Idioma:
Inglés
Revista:
An. bras. dermatol
Asunto de la revista:
Dermatologia
Año:
2016
Tipo del documento:
Artículo
País de afiliación:
Brasil
Institución/País de afiliación:
Universidade de São Paulo/BR
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