Biopharmaceuticals from microorganisms: from production to purification
Braz. j. microbiol
;
47(supl.1): 51-63, Oct.-Dec. 2016. tab, graf
Artículo
en Inglés
| LILACS
| ID: biblio-839328
ABSTRACT
ABSTRACT The use of biopharmaceuticals dates from the 19th century and within 5-10 years, up to 50% of all drugs in development will be biopharmaceuticals. In the 1980s, the biopharmaceutical industry experienced a significant growth in the production and approval of recombinant proteins such as interferons (IFN α, β, and γ) and growth hormones. The production of biopharmaceuticals, known as bioprocess, involves a wide range of techniques. In this review, we discuss the technology involved in the bioprocess and describe the available strategies and main advances in microbial fermentation and purification process to obtain biopharmaceuticals.
Texto completo:
Disponible
Índice:
LILACS (Américas)
Asunto principal:
Productos Biológicos
/
Biotecnología
/
Preparaciones Farmacéuticas
/
Técnicas Microbiológicas
Idioma:
Inglés
Revista:
Braz. j. microbiol
Asunto de la revista:
Microbiologia
Año:
2016
Tipo del documento:
Artículo
País de afiliación:
Brasil
Institución/País de afiliación:
Universidade de Sorocaba/BR
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