Comprehensive neuropsychological evaluation of children and adolescents with sickle cell anemia: a hospital-based sample
Rev. bras. hematol. hemoter
;
39(1): 32-39, Jan.-Mar. 2017. tab
Artículo
en Inglés
| LILACS
| ID: biblio-843951
ABSTRACT
Abstract Background:
Individuals with sickle cell anemia may suffer symptomatic or silent cerebral infarcts leading to neurocognitive complications. This study investigated the cognitive and intellectual performance of children and adolescents with sickle cell anemia.Methods:
The socioeconomic status, clinical aspects and behavioral profile of 15 young individuals with sickle cell anemia were evaluated. The Wechsler Intelligence Scale for Children, the Developmental Neuropsychological Assessment Test, and the Child Behavior Checklist were applied.Results:
Participants with a history of stroke had lower intelligence quotient (IQ) scores. Alterations were found in attention and executive functioning, language, verbal and visual memory, visuospatial processing and sensorimotor skills. These alterations were found both in the children and adolescents who had had a cerebral infarction and in those who apparently had not. In the majority of cases, there were learning difficulties, a history of repeating school years and a need for specialist educational support. The most common additional diagnoses in accordance with the Diagnostic and Statistical Manual of Mental Disorders IV were depressive disorder, anxiety disorder and somatic disorder, as well as conditions associated with physical and psychosocial repercussions of sickle cell anemia.Conclusion:
As sickle cell anemia is considered a progressive cerebral vasculopathy, it is a potential risk factor for neurocognitive and psychosocial development. Therefore, periodic neuropsychological and behavioral evaluations of children and adolescents with sickle cell anemia may represent a useful measure to reduce long-term biopsychosocial repercussions.
Texto completo:
Disponible
Índice:
LILACS (Américas)
Asunto principal:
Manifestaciones Neuroconductuales
/
Pruebas de Inteligencia
/
Anemia de Células Falciformes
/
Pruebas Neuropsicológicas
Tipo de estudio:
Guía de Práctica Clínica
/
Factores de riesgo
Idioma:
Inglés
Revista:
Rev. bras. hematol. hemoter
Asunto de la revista:
Hematología
Año:
2017
Tipo del documento:
Artículo
País de afiliación:
Brasil
Institución/País de afiliación:
Universidade Federal da Bahia/BR
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