Periodontopathogens, Candida spp. and immunological aspects in type 2 diabetes mellitus patients with chronic periodontitis
Braz. j. oral sci
;
15(3)July-Sept. 2016. ilus
Artículo
en Inglés
| LILACS, BBO
| ID: biblio-875096
ABSTRACT
This study aimed to evaluate clinical, microbiological and immunological parameters in type 2 diabetes mellitus (DM) in comparison with normoglycemic patients (NDM). Glycemic and lipid profiles and periodontal clinical status were determined for thirty-three patients (17 DM and 16 NDM). The presence of periodontopathogens and species of Candida in subgingival sites were determined by polymerase chain reaction and immunological parameters by ELISA assays. All glycemic and clinical parameters evaluated were higher in the DM group, with statistical difference for fasting glucose, glycated-hemoglobin, and periodontal parameters. Lipid profile (except triglycerides), levels of TNF-α and myeloperoxidase and the prevalence of the tested microorganisms were similar between the groups, except for Candida albicans and Candida glabrata, which was higher in the DM group. In conclusion, although microbiological and immunological parameters were similar in the DM and NDM groups, periodontitis and the levels of some species of Candida were more severe in DM patients. (AU)
Texto completo:
Disponible
Índice:
LILACS (Américas)
Asunto principal:
Enfermedades Periodontales
/
Factor de Necrosis Tumoral alfa
/
Peroxidasa
/
Diabetes Mellitus Tipo 2
/
Periodontitis Crónica
Tipo de estudio:
Factores de riesgo
Límite:
Femenino
/
Humanos
/
Masculino
Idioma:
Inglés
Revista:
Braz. j. oral sci
Asunto de la revista:
Odontología
Año:
2016
Tipo del documento:
Artículo
País de afiliación:
Brasil
Institución/País de afiliación:
Federal University of Rio de Janeiro/BR
/
Fluminense Federal University/BR
/
Univ Estadual Paulista/BR
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