Fluorescent test accurately predicts leak of ischemic colon anastomosis in rats
Acta cir. bras
;
32(6): 440-448, June 2017. tab, graf
Artículo
en Inglés
| LILACS
| ID: biblio-886209
ABSTRACT
Abstract Purpose:
To investigate if fluorescein fluorescent test can predict dehiscence in a model of ischemic colonic anastomosis in rats.Methods:
This experimental controlled trial randomly assigned 55 rats to four groups. Anastomoses were performed in non-ischemic colon segments (control group) and in ischemic colon segments measuring 1, 2 or 3 cm long (groups 1, 2 and 3, respectively). Fluorescein was injected and the tissues were examined under ultraviolet light. Seven days later, a second-look surgery was performed to check for the presence or absence of anastomosis dehiscence.Results:
Twenty-four rats presented anastomotic dehiscence during the second-look surgery. Reticular and nonfluorescent patterns were significantly associated with the occurrence of anastomotic dehiscence. Fluorescein fluorescence had a sensitivity of 95.8%, specificity of 89.2%, positive predictive value of 88.4%, negative predictive value of 96.2%, and accuracy of 92.3% to predict anastomotic dehiscence.Conclusion:
Fluorescein fluorescent test can accurately predict leak in a model of ischemic colonic anastomosis in rats.
Texto completo:
Disponible
Índice:
LILACS (Américas)
Asunto principal:
Dehiscencia de la Herida Operatoria
/
Anastomosis Quirúrgica
/
Colon
/
Fluoresceína
/
Colorantes Fluorescentes
/
Isquemia
Tipo de estudio:
Estudio pronóstico
/
Factores de riesgo
Límite:
Animales
Idioma:
Inglés
Revista:
Acta cir. bras
Asunto de la revista:
Cirugía General
/
Procedimentos Cir£rgicos Operat¢rios
Año:
2017
Tipo del documento:
Artículo
País de afiliación:
Brasil
Institución/País de afiliación:
Universidade Federal do Rio Grande do Sul/BR
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