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Immune System Dysfunction in the Elderly
FUENTES, EDUARDO; FUENTES, MANUEL; ALARCÓN, MARCELO; PALOMO, IVÁN.
  • FUENTES, EDUARDO; Universidad de Talca. Faculty of Health Sciences. Department of Clinical Biochemistry and Immunohematology. Talca. CL
  • FUENTES, MANUEL; Universidad de Talca. Faculty of Health Sciences. Department of Clinical Biochemistry and Immunohematology. Talca. CL
  • ALARCÓN, MARCELO; Universidad de Talca. Faculty of Health Sciences. Department of Clinical Biochemistry and Immunohematology. Talca. CL
  • PALOMO, IVÁN; Universidad de Talca. Faculty of Health Sciences. Department of Clinical Biochemistry and Immunohematology. Talca. CL
An. acad. bras. ciênc ; 89(1): 285-299, Jan,-Mar. 2017. graf
Artículo en Inglés | LILACS | ID: biblio-886643
ABSTRACT
ABSTRACT Human aging is characterized by both physical and physiological frailty that profoundly affects the immune system. In this context aging is associated with declines in adaptive and innate immunity established as immunosenescence. Immunosenescence is a new concept that reflects the age-associated restructuring changes of innate and adaptive immune functions. Thus elderly individuals usually present chronic low-level inflammation, higher infection rates and chronic diseases. A study of alterations in the immune system during aging could provide a potentially useful biomarker for the evaluation of immune senescence treatment. The immune system is the result of the interplay between innate and adaptive immunity, yet the impact of aging on this function is unclear. In this article the function of the immune system during aging is explored.
Asunto(s)


Texto completo: Disponible Índice: LILACS (Américas) Asunto principal: Inmunosenescencia / Sistema Inmunológico / Enfermedades del Sistema Inmune Límite: Anciano / Aged80 / Humanos Idioma: Inglés Revista: An. acad. bras. ciênc Asunto de la revista: Ciencia Año: 2017 Tipo del documento: Artículo País de afiliación: Chile Institución/País de afiliación: Universidad de Talca/CL

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Texto completo: Disponible Índice: LILACS (Américas) Asunto principal: Inmunosenescencia / Sistema Inmunológico / Enfermedades del Sistema Inmune Límite: Anciano / Aged80 / Humanos Idioma: Inglés Revista: An. acad. bras. ciênc Asunto de la revista: Ciencia Año: 2017 Tipo del documento: Artículo País de afiliación: Chile Institución/País de afiliación: Universidad de Talca/CL