Skin disorders in renal transplant recipients: a retrospective study
An. bras. dermatol
;
92(5): 638-641, Sept.-Oct. 2017. tab
Artículo
en Inglés
| LILACS
| ID: biblio-887038
ABSTRACT
Abstract Background:
Immunosuppressive therapy, which is necessary to avoid graft rejection in renal transplant recipients, presents an increased risk of several pathologies, namely infectious and neoplastic.Objectives:
To identify the most frequent skin diseases and their clinical and demographical risk factors within a population of renal transplant recipients.Methods:
A retrospective study of renal transplant recipients referred to dermatology visit and observed for the first time from January 2008 to December 2014.Results:
The study included 197 patients, 120 men (60,9%). Mean age was 50,7 years (±13,4). 12 patients (6,1%) had previous skin cancer. Infections were the most frequent reason of referral (93/197; 44%). From the total referred, 18,3% (36/197) presented pre-cancerous lesions. Malignancy was diagnosed in 36 patients (18,3%), with 29 non-melanoma skin cancers (14,7%) and 7 Kaposi sarcomas (3,6%). Ratio of basal cell carcinoma to squamous cell carcinoma was 1,11. Non-melanoma skin cancer was significantly associated with older age (p = 0,002), male gender (p = 0,028), history of previous skin cancer (p = 0,002) and higher duration of immunosuppressive therapy (p<0,001). Studylimitations:
Retrospective study, with data from the first visit in dermatology. We didn't made classification on skin-types.Conclusions:
The great incidence of cutaneous infections and skin cancer is responsible for a significant morbidity. It is important to assure the regular dermatological follow-up of renal transplant recipients, which will promote the prevention, an early diagnosis and an efficient treatment.
Texto completo:
Disponible
Índice:
LILACS (Américas)
Asunto principal:
Enfermedades de la Piel
/
Terapia de Inmunosupresión
/
Trasplante de Riñón
Tipo de estudio:
Estudio de etiología
/
Estudio observacional
/
Estudio pronóstico
/
Factores de riesgo
/
Estudio de tamizaje
Límite:
Adulto
/
Anciano
/
Femenino
/
Humanos
/
Masculino
Idioma:
Inglés
Revista:
An. bras. dermatol
Asunto de la revista:
Dermatologia
Año:
2017
Tipo del documento:
Artículo
País de afiliación:
Portugal
Institución/País de afiliación:
Universidade de Lisboa/PT
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