Photodynamic action of the red laser on Propionibacterium acnes
An. bras. dermatol
;
92(5): 622-625, Sept.-Oct. 2017. tab, graf
Artículo
en Inglés
| LILACS
| ID: biblio-887046
ABSTRACT
Abstract Background:
Photodynamic therapy is a therapeutic modality that has consolidated its activity in the photooxidation of organic matter, which arises from the activity of reactive oxygen species.Objective:
To evaluate the effect of red laser 660nm with the photosensitizer methylene blue on Propionibacterium acnes in vitro.Method:
The experimental design was distributed into four groups (1 - control group without the application of light and without photosensitizer, 2 - application of light, 3 - methylene blue without light, and 4 - methylene blue with light). Tests were subjected to red laser irradiation 660nm by four cycles of 5 minutes at 3-minute intervals.Results:
It was evidenced the prominence of the fourth cycle (20 minutes) groups 2, 3 and 4. Studylimitations:
Despite the favorable results, the laser irradiation time photosensitizer associated with methylene blue were not sufficient to to completely inhibit the proliferation of bacteria.Conclusion:
Further studies in vitro are recommended to enable the clinical application of this photosensitizer in photodynamic therapy.
Texto completo:
Disponible
Índice:
LILACS (Américas)
Asunto principal:
Fotoquimioterapia
/
Propionibacterium acnes
/
Fármacos Fotosensibilizantes
/
Azul de Metileno
Límite:
Humanos
Idioma:
Inglés
Revista:
An. bras. dermatol
Asunto de la revista:
Dermatologia
Año:
2017
Tipo del documento:
Artículo
País de afiliación:
Brasil
Institución/País de afiliación:
Universidade Brasil/BR
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