Your browser doesn't support javascript.
loading
Related quality of life questionnaire specific to dysthyroid ophthalmopathy evaluated in a population of patients with Graves' disease
Delfino, Laura Carolina; Zunino, Anabela; Sapia, Verónica; Croome, María del Carmen Silva; Ilera, Verónica; Gauna, Alicia Teresa.
  • Delfino, Laura Carolina; Hospital de Agudos J. M. Ramos Mejía. Ciudad Autónoma de Buenos Aires. AR
  • Zunino, Anabela; Hospital de Agudos J. M. Ramos Mejía. Ciudad Autónoma de Buenos Aires. AR
  • Sapia, Verónica; Hospital de Agudos J. M. Ramos Mejía. Ciudad Autónoma de Buenos Aires. AR
  • Croome, María del Carmen Silva; Hospital de Agudos J. M. Ramos Mejía. Ciudad Autónoma de Buenos Aires. AR
  • Ilera, Verónica; Hospital de Agudos J. M. Ramos Mejía. Ciudad Autónoma de Buenos Aires. AR
  • Gauna, Alicia Teresa; Hospital de Agudos J. M. Ramos Mejía. Ciudad Autónoma de Buenos Aires. AR
Arch. endocrinol. metab. (Online) ; 61(4): 374-381, July-Aug. 2017. tab, graf
Artículo en Inglés | LILACS | ID: biblio-887568
ABSTRACT
ABSTRACT Objective The aim of this study was to measure quality of life (QOL) impairment in individuals currently suffering from Graves' ophthalmopathy (GO) and to determine the correlation of GO-specific QOL scores with disease severity and activity. Subjects and methods Seventy three GO-specific QOL surveys were prospectively analysed and compared with GO status. The GO-specific QOL survey was translated into Spanish and applied to Argentine patients with Graves' disease (GD). Results were compared with presence or absence of GO, Clinical Activity Score (CAS), severity score, age, gender and thyroid function. Results Fifty-six patients answered the survey and underwent complete ophthalmic evaluation, 15 did not have GO and were considered to be a control group. Appearance QOL score for patients with GO (53 ± 31.4) was lower than the control group (88.3 ± 17) (p < 0,000), no difference was observed in functional QOL score. There was a negative correlation between GO severity and both functional (r = -0.575; p < 0.000) and appearance QOL (r = -0.577; p < 0.000). Functional QOL differed between patients with active GO vs control group (p = 0.043). Patients with active and inactive GO had lower appearance QOL scores than control group (p < 0.000, p < 0.001 respectively). Conclusions GO has significant impact on the life of these Argentine patients. QOL was worse in GO patients than in control group, functional QOL was mostly affected by the activity and appearance QOL was mainly altered by the effects of the disease. Patients with more severe GO had lower scores on both QOL scales.
Asunto(s)


Texto completo: Disponible Índice: LILACS (Américas) Asunto principal: Calidad de Vida / Encuestas y Cuestionarios / Oftalmopatía de Graves Tipo de estudio: Estudio observacional / Estudio de prevalencia / Investigación cualitativa / Factores de riesgo Límite: Adulto / Femenino / Humanos / Masculino País/Región como asunto: America del Sur / Argentina Idioma: Inglés Revista: Arch. endocrinol. metab. (Online) Asunto de la revista: Endocrinologia / Metabolismo Año: 2017 Tipo del documento: Artículo País de afiliación: Argentina Institución/País de afiliación: Hospital de Agudos J. M. Ramos Mejía/AR

Similares

MEDLINE

...
LILACS

LIS


Texto completo: Disponible Índice: LILACS (Américas) Asunto principal: Calidad de Vida / Encuestas y Cuestionarios / Oftalmopatía de Graves Tipo de estudio: Estudio observacional / Estudio de prevalencia / Investigación cualitativa / Factores de riesgo Límite: Adulto / Femenino / Humanos / Masculino País/Región como asunto: America del Sur / Argentina Idioma: Inglés Revista: Arch. endocrinol. metab. (Online) Asunto de la revista: Endocrinologia / Metabolismo Año: 2017 Tipo del documento: Artículo País de afiliación: Argentina Institución/País de afiliación: Hospital de Agudos J. M. Ramos Mejía/AR