Synthesis and anti-myocarditis activity in a multifunctional lanthanide microporous metal-organic framework with 1D helical chain building units
Braz. j. med. biol. res
;
51(3): e7050, 2018. tab, graf
Artículo
en Inglés
| LILACS
| ID: biblio-889043
ABSTRACT
A new microporous lanthanide metal-organic framework, {[Yb(BTB)(H2O) (DEF)2}n (1, DEF=N,N-Diethylformamide), with 1D nano-sized channels has been constructed by bridging helical chain secondary building units with 1,3,5-benzenetrisbenzoic acid (H3BTB) ligand. Structural characterization suggests that this complex crystallizes in the hexagonal space group P6122 and possesses 1D triangular channels with coordinated water molecules pointing to the channel center. In addition, anti-myocarditis properties of compound 1 were evaluated in vivo. The results showed that compound 1 can improve hemodynamic parameters of, and it may be a good therapeutic option for heart failure in the future.
Texto completo:
Disponible
Índice:
LILACS (Américas)
Asunto principal:
Cristalografía por Rayos X
/
Elementos de la Serie de los Lantanoides
/
Estructuras Metalorgánicas
/
Antiinflamatorios
/
Miocarditis
Límite:
Animales
Idioma:
Inglés
Revista:
Braz. j. med. biol. res
Asunto de la revista:
Biologia
/
Medicina
Año:
2018
Tipo del documento:
Artículo
País de afiliación:
China
Institución/País de afiliación:
Wenzhou Medical University/CN
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