Phage therapy: progress in pharmacokinetics
Braz. J. Pharm. Sci. (Online)
;
54(1): e17093, 2018. tab, graf
Artículo
en Inglés
| LILACS
| ID: biblio-889446
ABSTRACT
ABSTRACT The concept of phage therapy exists in the history and it has been ignored for a long time, but the consequence of drug resistance in pathogen bacteria has forced the forgotten kingdom of phage therapy to be re-explored. However, for the successful implementation and acceptance of phage therapy worldwide, the number of factors need to be addressed. In pharmacology of phage therapy, pharmacodynamics is a straightforward concept, on the other hand, owing to the unique feature of phages to replicate and their high sensitivity, pharmacokinetics is rather complex. In this review, we have discussed pharmacokinetics and some recent advances in delivery systems as to achieve the therapeutically effective concentrations of phage in their activated form.
Texto completo:
Disponible
Índice:
LILACS (Américas)
Asunto principal:
Terapéutica
/
Bacteriófagos
Idioma:
Inglés
Revista:
Braz. J. Pharm. Sci. (Online)
Asunto de la revista:
Farmacologia
/
Teraputica
/
Toxicologia
Año:
2018
Tipo del documento:
Artículo
País de afiliación:
Pakistán
Institución/País de afiliación:
Bahauddin Zakariya University/PK
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