Risk factors and comorbidities in Brazilian patients with orofacial clefts
Braz. oral res. (Online)
; 32: e24, 2018. tab
Article
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| ID: biblio-889479
Biblioteca responsable:
BR1.1
ABSTRACT
Abstract Considering that environmental risk factors substantially contribute to the etiology of orofacial clefts and that knowledge about the characteristics and comorbidities associated with oral clefts is fundamental to promoting better quality of life, this study aimed to describe the risk factors, main characteristics, and comorbidities of a group of patients with cleft lip and/or cleft palate (CL/P) from Rio Grande do Norte (RN), Brazil. Data were obtained from 173 patients with CL/P using a form from the Brazilian database on Orofacial Clefts. Most patients were male with cleft lip and palate and had a normal size and weight at birth; presented few neonatal intercurrent events; and had anemia and respiratory and cardiovascular diseases as main associated comorbidities. They also required timely surgical rehabilitation and multidisciplinary care to stimulate their neuropsychomotor development. In addition, a high frequency of familial recurrence and of parental consanguinity was evidenced in the studied population, especially for the cleft lip and cleft palate type. Other relevant findings were the considerable maternal exposure to alcohol, infections, smoking, and hypertension, as well as low supplementation with vitamins and minerals and deliberate consumption of analgesics, antibiotics, and antihypertensives during pregnancy. Characterization of the CL/P patient profile is essential for the planning of health services and integration among the health professionals involved in the diagnosis and treatment of these malformations. Our results reinforce the need for additional research to confirm the association between environmental factors and the development of orofacial clefts.
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Texto completo:
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Índice:
LILACS
Asunto principal:
Labio Leporino
/
Fisura del Paladar
Tipo de estudio:
Etiology_studies
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Prevalence_studies
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Risk_factors_studies
Límite:
Adolescent
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Adult
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Child
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Child, preschool
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Female
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Humans
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Infant
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Male
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Pregnancy
País/Región como asunto:
America do sul
/
Brasil
Idioma:
En
Revista:
BOR
/
Braz Oral Res
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Braz oral res
/
Braz. oral res
/
Braz. oral res. (Online)
/
Brazilian Oral Research (Online)
/
Brazilian oral research
/
Brazilian oral research (Impresso)
Asunto de la revista:
ODONTOLOGIA
Año:
2018
Tipo del documento:
Article