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Effectiveness and durability of solifenacin versus percutaneous tibial nerve stimulation versus their combination for the treatment of women with overactive bladder syndrome: a randomized controlled study with a follow-up of ten months
Vecchioli-Scaldazza, Carlo; Morosetti, Carolina.
  • Vecchioli-Scaldazza, Carlo; ASUR. Division of Urogynecology. Jesi. IT
  • Morosetti, Carolina; ASUR. Division of Urogynecology. Jesi. IT
Int. braz. j. urol ; 44(1): 102-108, Jan.-Feb. 2018. tab
Artículo en Inglés | LILACS | ID: biblio-892947
ABSTRACT
ABSTRACT Purpose To assess effectiveness and durability of Solifenacin (SS) versus tibial nerve stimulation (PTNS) versus combination therapy (PTNS + SS) in women with overactive bladder syndrome (OAB). Materials and Methods 105 women with OAB were divided randomly into three groups of 35 patients each. In group A women received SS, in group B women underwent PTNS, in group C women underwent combination of PTNS + SS. Improvements in OAB symptoms were assessed with OABSS questionnaire; patients' quality of life was assessed with OAB-q SF questionnaire. Evaluation of effectiveness of treatments was performed with PGI-I questionnaire. OABSS and PGI-I were also assessed monthly for ten months. Results All treatments were effective on symptoms. PTNS showed a greater effectiveness than SS, but PTNS + SS was more effective than SS and PTNS. Furthermore, PTNS + SS showed a greater duration of effectiveness than PTNS and SS. Conclusions Combination of PTNS with SS showed more effectiveness and more durability than PTNS and SS alone.
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Texto completo: Disponible Índice: LILACS (Américas) Asunto principal: Estimulación Eléctrica Transcutánea del Nervio / Vejiga Urinaria Hiperactiva / Agentes Urológicos / Succinato de Solifenacina Tipo de estudio: Ensayo Clínico Controlado / Estudio observacional / Estudio pronóstico / Factores de riesgo Límite: Adulto / Femenino / Humanos Idioma: Inglés Revista: Int. braz. j. urol Asunto de la revista: Urología Año: 2018 Tipo del documento: Artículo País de afiliación: Italia Institución/País de afiliación: ASUR/IT

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Texto completo: Disponible Índice: LILACS (Américas) Asunto principal: Estimulación Eléctrica Transcutánea del Nervio / Vejiga Urinaria Hiperactiva / Agentes Urológicos / Succinato de Solifenacina Tipo de estudio: Ensayo Clínico Controlado / Estudio observacional / Estudio pronóstico / Factores de riesgo Límite: Adulto / Femenino / Humanos Idioma: Inglés Revista: Int. braz. j. urol Asunto de la revista: Urología Año: 2018 Tipo del documento: Artículo País de afiliación: Italia Institución/País de afiliación: ASUR/IT