Oral cancer stem cells - properties and consequences
J. appl. oral sci
;
25(6): 708-715, Nov.-Dec. 2017. graf
Artículo
en Inglés
| LILACS, BBO
| ID: biblio-893672
ABSTRACT
Abstract Research on cancer stem cells (CSCs) has greatly increased in the field of medicine and pathology; however, some conceptual misunderstandings are still present among the public as well as within the general scientific community that is not yet familiar with the subject. The very first problem is the misinterpretation of CSCs as a synonym of their normal counterparts, the well-known stem cells (SCs). Particularly in Dentistry, another common mistake is the misinterpretation of oral CSCs as normal tooth-derived SCs. The present review aims to clarify important concepts related to normal SCs and CSCs, as well as discuss the relevance of CSCs to the development, metastasis and therapy resistance of oral squamous cell carcinoma.
Texto completo:
Disponible
Índice:
LILACS (Américas)
Asunto principal:
Células Madre Neoplásicas
/
Neoplasias de la Boca
/
Carcinoma de Células Escamosas
Límite:
Humanos
Idioma:
Inglés
Revista:
J. appl. oral sci
Asunto de la revista:
Odontología
Año:
2017
Tipo del documento:
Artículo
País de afiliación:
Brasil
Institución/País de afiliación:
Universidade de São Paulo/BR
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