RNA viruses in trypanosomatid parasites: a historical overview
Mem. Inst. Oswaldo Cruz
;
113(4): e170487, 2018. graf
Artículo
en Inglés
| LILACS
| ID: biblio-894910
ABSTRACT
Viruses of trypanosomatids are now being extensively studied because of their diversity and the roles they play in flagellates' biology. Among the most prominent examples are leishmaniaviruses implicated in pathogenesis of Leishmania parasites. Here, we present a historical overview of this field, starting with early reports of virus-like particles on electron microphotographs, and culminating in detailed molecular descriptions of viruses obtained using modern next generation sequencing-based techniques. Because of their diversity, different life cycle strategies and host specificity, we believe that trypanosomatids are a fertile ground for further explorations to better understand viral evolution, routes of transitions, and molecular mechanisms of adaptation to different hosts.
Texto completo:
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Índice:
LILACS (Américas)
Asunto principal:
Virus ARN
/
Trypanosomatina
/
Microscopía Electrónica de Transmisión de Rastreo
/
Leishmaniavirus
Idioma:
Inglés
Revista:
Mem. Inst. Oswaldo Cruz
Asunto de la revista:
Medicina Tropical
/
Parasitología
Año:
2018
Tipo del documento:
Artículo
/
Documento de proyecto
País de afiliación:
República Checa
Institución/País de afiliación:
University of Ostrava/CZ
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