Effect of different levels of peep on oxygenation during non-invasive ventilation in patients submitted to cabg surgery: randomized clinical trial
Rev. bras. cir. cardiovasc
;
32(4): 295-300, July-Aug. 2017. tab, graf
Artículo
en Inglés
| LILACS
| ID: biblio-897926
ABSTRACT
Abstract Introduction:
During and after coronary artery bypass grafting, a decline in multifactor lung function is observed. Due to this fact, some patients may benefit from non-invasive ventilation after extubation targeting lung expansion and consequently improved oxygenation.Objective:
To test the hypothesis that higher levels of positive end expiration pressure during non-invasive ventilation improves oxygenation in patients undergoing coronary artery bypass grafting.Methods:
A randomized clinical trial was conducted at Instituto Nobre de Cardiologia in Feira de Santana. On the first day after surgery, the patients were randomized Group PEEP 10, Group PEEP 12 and Group PEEP 15 who underwent non-invasive ventilation with positive end expiration pressure level. All patients were submitted to analysis blood pressure oxygen (PaO2), arterial oxygen saturation (SaO2) and oxygenation index (PaO2/FiO2).Results:
Thirty patients were analyzed, 10 in each group, with 63.3% men with a mean age of 61.1±12.2 years. Mean pulmonary expansion pre-therapy PaO2 was generally 121.9±21.6 to 136.1±17.6 without statistical significance in the evaluation among the groups. This was also present in PaO2/FiO2 and SaO2. Statistical significance was only present in pre and post PEEP 15 when assessing the PaO2 and SaO2 (P=0.02).Conclusion:
Based on the findings of this study, non-invasive ventilation with PEEP 15 represented an improvement in oxygenation levels of patients undergoing coronary artery bypass grafting.
Texto completo:
Disponible
Índice:
LILACS (Américas)
Asunto principal:
Oxígeno
/
Intercambio Gaseoso Pulmonar
/
Puente de Arteria Coronaria
/
Respiración con Presión Positiva
/
Ventilación no Invasiva
Tipo de estudio:
Ensayo Clínico Controlado
Límite:
Anciano
/
Femenino
/
Humanos
/
Masculino
Idioma:
Inglés
Revista:
Rev. bras. cir. cardiovasc
Asunto de la revista:
Cardiología
/
Cirugía General
Año:
2017
Tipo del documento:
Artículo
País de afiliación:
Brasil
Institución/País de afiliación:
Escola Bahiana de Medicina e Saúde Pública/BR
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