A Nexus model of cellular transition in cancer
Biol. Res
;
51: 23, 2018. tab, graf
Artículo
en Inglés
| LILACS
| ID: biblio-950911
ABSTRACT
The exact cause of cancer is one of the most immutable medical questions of the century. Cancer as an evolutionary disease must have a purpose and understanding the purpose is more important than decoding the cause. The model of cancer proposed herein, provides a link between the cellular biochemistry and cellular genetics of cancer evolution. We thus call this model as the "Nexus model" of cancer. The Nexus model is an effort to identify the most apparent route to the disease. We have tried to utilize existing cancer literature to identify the most plausible causes of cellular transition in cancer, where the primary cancer-causing agents (physical, chemical or biological) act as inducing factors to produce cellular impeders. These cellular impeders are further linked to the Nexus. The Nexus then generates codes for epigenetics and genetics in cancer development.
Texto completo:
Disponible
Índice:
LILACS (Américas)
Asunto principal:
Transformación Celular Neoplásica
/
Epigénesis Genética
/
Carcinogénesis
/
Modelos Biológicos
/
Neoplasias
Tipo de estudio:
Estudio pronóstico
Límite:
Humanos
Idioma:
Inglés
Revista:
Biol. Res
Asunto de la revista:
Biologia
Año:
2018
Tipo del documento:
Artículo
País de afiliación:
India
Institución/País de afiliación:
Softvision College and Research Institute/IN
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