Antihypoxic activities of Crataegus pentaegyn and Crataegus microphylla fruits-an in vivo assay
Braz. J. Pharm. Sci. (Online)
;
54(2): e17363, 2018. tab
Artículo
en Inglés
| LILACS
| ID: biblio-951923
ABSTRACT
ABSTRACT The aim of this study was to evaluate anti-hypoxia activity of polyphenolic extracts of Crataegus microphylla and Crataegus pentaegyn on mice. Three experimental models of hypoxia were considered, including asphyctic hypoxia, haemic hypoxia, and circulatory hypoxia. Polyphenolic extract of both plants exhibited significant anti-hypoxic activity and prolonged animal survival time. Anti-hypoia activity of C. pentaegyn was found to be superior to that of C. microphylla in circulatory and asphyctic hypoxia. Antihypoxic activity of these extracts may be attributed to their phenolic compounds.
Texto completo:
Disponible
Índice:
LILACS (Américas)
Asunto principal:
Crataegus
/
Hipoxia
Límite:
Animales
Idioma:
Inglés
Revista:
Braz. J. Pharm. Sci. (Online)
Asunto de la revista:
Farmacologia
/
Teraputica
/
Toxicologia
Año:
2018
Tipo del documento:
Artículo
País de afiliación:
Irán
Institución/País de afiliación:
Golestan University of Medical Sciences/IR
/
Mazandaran University of Medical Sciences/IR
/
Tehran University of Medical Sciences/IR
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