Pituitary gland volumes in patients with obsessive-compulsive disorder before and after cognitive-behavioral therapy
Braz. J. Psychiatry (São Paulo, 1999, Impr.)
;
40(4): 420-423, Oct.-Dec. 2018. tab, graf
Artículo
en Inglés
| LILACS
| ID: biblio-959265
ABSTRACT
Objective:
The beneficial effects of psychopharmacological and cognitive behavioral therapy (CBT) on the brain are not well understood. In a previous study, we found smaller pituitary volumes in patients with obsessive-compulsive disorder (OCD). The purpose of this study was to examine the effect of CBT on pituitary gland volume.Methods:
A total of 81 patients with various anxiety disorders and the same number of healthy controls underwent magnetic resonance imaging, and their pituitary gland volumes were compared at baseline. Pituitary gland volumes were also measured before and after CBT in the patient group.Results:
OCD patients had smaller pituitary gland volumes at baseline than healthy controls (0.54±0.29 cm3 for OCD patients vs. 0.82±0.30 cm3 for healthy controls; p < 0.001). We found no significant changes in OCD patient pituitary gland volume after the 16-week treatment period, with mean pre- and post-treatment values of 0.54±0.29 cm3 and 0.56±0.32 cm3, respectively (p > 0.05).Conclusion:
Our results indicate an absence of post-CBT volumetric changes in the pituitary gland of OCD patients.
Texto completo:
Disponible
Índice:
LILACS (Américas)
Asunto principal:
Hipófisis
/
Terapia Cognitivo-Conductual
/
Trastorno Obsesivo Compulsivo
Límite:
Adulto
/
Femenino
/
Humanos
/
Masculino
Idioma:
Inglés
Revista:
Braz. J. Psychiatry (São Paulo, 1999, Impr.)
Asunto de la revista:
Psiquiatria
Año:
2018
Tipo del documento:
Artículo
País de afiliación:
Turquía
Institución/País de afiliación:
Elazig Mental Health Hospital/TR
/
Firat University/TR
/
Hasan Kalyoncu University/TR
/
Tokat State Hospital/TR
/
Yildirim Beyazit Dışkapı Training and Research Hospital/TR
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