Disglucemia asociada a fluoroquinolonas: una revisión estructurada / Hypo or hyperglycemia associated with fluoroquinolone use
Rev. méd. Chile
; 146(5): 618-626, mayo 2018. tab, graf
Article
en Es
| LILACS
| ID: biblio-961438
Biblioteca responsable:
CL1.1
ABSTRACT
Fluoroquinolone type antimicrobials can cause hypo or hyperglycemia in certain patients. We performed a structured review about this side effect, searching articles published in English or Spanish with full text access in PubMed/Medline. The following MESH terms were used Hypoglycemia, Hyperglycemia, Quinolones, Ciprofloxacin, Levofloxacin, Moxifloxacin. Additionally, we evaluated the clinical relevance of potential drug interactions, based on the probability of occurrence and the severity of the interaction effect. We obtained 42 publications about the issue; 22 references were selected, where the severity of the interaction in patients with risk factors was evaluated. Patients receiving antidiabetic medications and with risk factors such as advanced age and renal failure may be more likely to have a severe hypoglycemia. In these patients, this drug interaction should be considered clinically relevant since its risk is high or very high.
Palabras clave
Texto completo:
1
Índice:
LILACS
Asunto principal:
Fluoroquinolonas
/
Diabetes Mellitus
/
Hiperglucemia
/
Hipoglucemia
Tipo de estudio:
Risk_factors_studies
Límite:
Humans
Idioma:
Es
Revista:
Rev. méd. Chile
Asunto de la revista:
MEDICINA
Año:
2018
Tipo del documento:
Article