Stereological and morphological analysis of the effects of aging on spermatogenesis in rat testis
Acta cir. bras
;
33(10): 904-913, Oct. 2018. tab, graf
Artículo
en Inglés
| LILACS
| ID: biblio-973466
ABSTRACT
Abstract Purpose:
To quantify, through stereological and morphometric analysis, spermatogenesis in rats undergoing the natural aging process.Methods:
Seventy-two male Wistar rats were divided into 6 equal groups according to age at the time of killing 3, 6, 9, 12, 18, and 24 months. All the rats were subjected orchiectomy and collection of testicular parenchymal fragments for histological and morphometric analysis. The numerical density of spermatids was calculated using a stereological study, and morphometric analysis was conducted to measure the height of the germinal epithelium and the area of the seminiferous tubules.Results:
We found that the 18 and 24 months groups showed a significant reduction in the number of round spermatids. However, the height of the germinal epithelium was not significantly different between the groups. The area of seminiferous tubules was also significantly reduced in the elderly rats compared to that in the young ones.Conclusion:
Aging of rats showed a significant reduction in the number of round spermatids and the area of the seminiferous tubules, more pronounced in the rats at 18 and 24 months of life.
Texto completo:
Disponible
Índice:
LILACS (Américas)
Asunto principal:
Túbulos Seminíferos
/
Espermátides
/
Espermatogénesis
/
Envejecimiento
Límite:
Animales
Idioma:
Inglés
Revista:
Acta cir. bras
Asunto de la revista:
Cirugía General
/
Procedimentos Cir£rgicos Operat¢rios
Año:
2018
Tipo del documento:
Artículo
País de afiliación:
Brasil
Institución/País de afiliación:
UFPR/BR
/
Universidade Federal do Paraná/BR
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