Effects of different periods of gastric ischemia on liver as a remote organ
Acta cir. bras
;
33(11): 964-974, Nov. 2018. tab, graf
Artículo
en Inglés
| LILACS
| ID: biblio-973473
ABSTRACT
Abstract Purpose: To evaluate the hepatic changes associated with gastric ischemia. Methods: Thirty male rabbits were studied, distributed in 3 groups (n=10). Group 1: ligature and section of the gastric vasculature and removal of the liver after three hours; Group 2: ligature and section of the gastric vasculature and removal of the liver after 6 hours; Group 3: ligature and section of the gastric vasculature and removal of the liver after 12 hours. Blood samples were collected immediately before surgery and after the determined time of ischemia in each group to evaluate the hepatic function. After the death of the rabbits, the liver was removed for macro and microscopic study. Results: An increase in aminotransferases and bilirubin occurred in groups 2 and 3. Total protein and albumin diminished in all of the animals. All of the rabbits from groups 2 and 3 presented hepatocellular necrosis. Conclusion: The devascularization of the stomach for a period of above three hours is associated with hepatic morphological and functional disorders.
Texto completo:
Disponible
Índice:
LILACS (Américas)
Asunto principal:
Estómago
/
Isquemia
/
Hígado
Tipo de estudio:
Estudio de etiología
Límite:
Animales
Idioma:
Inglés
Revista:
Acta cir. bras
Asunto de la revista:
Cirugía General
/
Procedimentos Cir£rgicos Operat¢rios
Año:
2018
Tipo del documento:
Artículo
País de afiliación:
Brasil
Institución/País de afiliación:
Faculdade Evangélica do Paraná/BR
/
UFMG/BR
/
Universidade Federal de Minas Gerais/BR
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