Influence of tramadol on functional recovery of acute spinal cord injury in rats
Acta cir. bras
;
33(12): 1087-1094, Dec. 2018. tab, graf
Artículo
en Inglés
| LILACS
| ID: biblio-973483
ABSTRACT
Abstract Purpose: To evaluate the influence tramadol on functional recovery of acute spinal cord injury in rats. Methods: Ten rats were divided into two groups (n = 5). All animals were submitted by a laminectomy and spinal cord injury at eighth thoracic vertebra. In control group, the rats didn't receive any analgesic. In tramadol group, the rats received tramadol 4mg/Kg at 12/12h until 5 days by subcutaneous. Animals were following by fourteen days. Was evaluated the Basso, Beattie, Bresnahan scale (locomotor evaluation) and Rat Grimace Scale (pain evaluation) at four periods. Results: There no difference between the groups in locomotor evaluation in all periods evaluated (p>0.05) and in both groups there was a partial recover of function. The tramadol group show a lower pain levels at the first, third and seventh postoperatively days when comparing to the control group. Conclusion: The tramadol as an analgesic agent don't influence on functional recovery of acute spinal cord injury in rats
Texto completo:
Disponible
Índice:
LILACS (Américas)
Asunto principal:
Traumatismos de la Médula Espinal
/
Tramadol
/
Recuperación de la Función
/
Analgésicos Opioides
Tipo de estudio:
Estudios de evaluación
Límite:
Animales
Idioma:
Inglés
Revista:
Acta cir. bras
Asunto de la revista:
Cirugía General
/
Procedimentos Cir£rgicos Operat¢rios
Año:
2018
Tipo del documento:
Artículo
País de afiliación:
Brasil
Institución/País de afiliación:
CESUPA/BR
/
Centro Universitário do Estado do Pará/BR
/
UEPA/BR
/
UFRA/BR
/
Universidade Federal Rural da Amazônia/BR
/
Universidade Federal do Pará/BR
/
Universidade do Estado do Pará/BR
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