Hyperbaric oxygenation on adhesions prevention after laparotomy in rats
Acta cir. bras
;
33(9): 824-833, Sept. 2018. tab, graf
Artículo
en Inglés
| LILACS
| ID: biblio-973497
ABSTRACT
Abstract Purpose:
To evaluate the effects of hyperbaric oxygenation on prevention of adhesions in the abdominal cavity after laparotomy.Methods:
Fifty four rats underwent laparotomy; stitches were made in the four quadrant parietal peritoneum and abdominal cavity closure. Animals were divided into three groups 1 - control; 2 - subjected to high pressures and oxygenation; 3 - subjected to 100% hyperbaric oxygenation. The animals in groups 2 and 3 were daily submitted to oxygenation hyperbaric chamber after surgery. On the seventh day another laparotomy, registration of procedure, assessment of adhesions and biopsies of the peritoneum were held. Professionals analyzed the videos and the biopsies.Results:
Peritoneal cavity adhesions occurred in animals of three groups with no difference between them. In Group 3, the adhesions presented more fragile and vascular proliferation more pronounced, and there was no difference in comparison with the first and second groups. However, there was no significant difference in the evaluation of these parameters between the animals in groups 1 and 2.Conclusions:
Postoperative hyperbaric oxygenation in rats submitted to laparotomy did not alter the frequency, but reduced the density of adhesions in the peritoneal cavity and promoted vascular proliferation. The change in atmospheric pressure alone had no influence on the results.
Texto completo:
Disponible
Índice:
LILACS (Américas)
Asunto principal:
Cavidad Peritoneal
/
Complicaciones Posoperatorias
/
Adherencias Tisulares
/
Oxigenoterapia Hiperbárica
Límite:
Animales
Idioma:
Inglés
Revista:
Acta cir. bras
Asunto de la revista:
Cirugía General
/
Procedimentos Cir£rgicos Operat¢rios
Año:
2018
Tipo del documento:
Artículo
País de afiliación:
Brasil
Institución/País de afiliación:
Hyperbaric Medicine/BR
/
UFMG/BR
/
Universidade Federal de Minas Gerais/BR
Similares
MEDLINE
...
LILACS
LIS