The influenza season 2016/17 in Bucharest, Romania - surveillance data and clinical characteristics of patients with influenza-like illness admitted to a tertiary infectious diseases hospital
Braz. j. infect. dis
;
22(5): 377-386, Sept.-Oct. 2018. tab, graf
Artículo
en Inglés
| LILACS
| ID: biblio-974239
ABSTRACT
ABSTRACT Background:
Influenza continues to drive seasonal morbidity, particularly in settings with low vaccine coverage.Objectives:
To describe the influenza cases and viral circulation among hospitalized patients.Methods:
A prospective study based on active surveillance of inpatients with influenza-like illness from a tertiary hospital in Bucharest, Romania, in the season 2016/17.Results:
A total of 446 patients were tested, with a balanced gender distribution. Overall, 192 (43%) patients tested positive for influenza, with the highest positivity rate in the age groups 3-13 years and >65 years. Peak activity occurred between weeks 1 and 16/2017, with biphasic distribution A viruses were replaced by B viruses from week 9/2017; B viruses predominated (66.1%). Among the 133 (69.3%) subtyped samples, all influenza A were subtype H3 (n = 57) and all influenza B were B/Victoria (n = 76). Patients who tested positive for influenza presented fewer comorbidities (p = 0.012), except for the elderly, in whom influenza was more common in patients with comorbidities (p = 0.050). Disease evolution was generally favorable under antiviral treatment. The length of hospital stay was slightly longer in patients with influenza-like illness who tested patients negative for influenza (p = 0.031).Conclusions:
Distinctive co-circulation of A/H3 and B/Victoria in Bucharest, Romania in the 2016/17 influenza season was found. While the A/H3 subtype was predominant throughout Europe that season, B/Victoria appears to have circulated specifically in Romania and the Eastern European region, predominantly affecting preschoolers and school children.
Texto completo:
Disponible
Índice:
LILACS (Américas)
Asunto principal:
Estaciones del Año
/
Síndrome Respiratorio Agudo Grave
/
Gripe Humana
/
Monitoreo Epidemiológico
Tipo de estudio:
Estudio observacional
/
Factores de riesgo
/
Estudio de tamizaje
Límite:
Adolescente
/
Adulto
/
Anciano
/
Niño
/
Child, preschool
/
Femenino
/
Humanos
/
Lactante
/
Masculino
País/Región como asunto:
Europa
Idioma:
Inglés
Revista:
Braz. j. infect. dis
Asunto de la revista:
Enfermedades Transmisibles
Año:
2018
Tipo del documento:
Artículo
País de afiliación:
Rumanía
Institución/País de afiliación:
Cantacuzino Military-Medical Research-Development National Institute/RO
/
National Institute for Infectious Diseases "Prof. Dr. Matei Balș"/RO
Similares
MEDLINE
...
LILACS
LIS