Impact of 68GA-PSMA PET / CT on treatment of patients with recurrent / metastatic high risk prostate cancer - a multicenter study
Int. braz. j. urol
;
44(5): 892-899, Sept.-Oct. 2018. tab, graf
Artículo
en Inglés
| LILACS
| ID: biblio-975631
ABSTRACT
ABSTRACT Purpose:
The purpose of our study was to evaluate the clinical impact of 68Ga-PSMA PET / CT in the setting of biochemical recurrence of prostate cancer. Materials andMethods:
We retrospectively evaluated 125 prostate cancer patients submitted to the 68Ga-PSMA PET / CT due to biochemical recurrence. The parameters age, Gleason score, PSA levels, and the highest SUVmax were correlated to potential treatment changes. The highest SUVmax values were correlated with age and Gleason score. The median follow-up time was 24 months.Results:
68Ga-PSMA PET / CT led to a treatment change in 66 / 104 (63.4%) patients (twenty-one patients were lost to follow-up). There was a significant change of treatment plan in patients with a higher Gleason score (P = 0.0233), higher SUVmax (p = 0.0306) and higher PSA levels (P < 0.0001; median PSA = 2.55 ng / mL).Conclusion:
68Ga-PSMA PET / CT in prostate cancer patients with biochemical recurrence has a high impact in patient management.
Texto completo:
Disponible
Índice:
LILACS (Américas)
Asunto principal:
Oligopéptidos
/
Neoplasias de la Próstata
/
Ácido Edético
/
Antígeno Prostático Específico
/
Tomografía Computarizada por Tomografía de Emisión de Positrones
/
Recurrencia Local de Neoplasia
Tipo de estudio:
Estudio diagnóstico
/
Estudio de etiología
/
Estudio observacional
/
Estudio pronóstico
/
Factores de riesgo
Límite:
Adulto
/
Anciano
/
Aged80
/
Humanos
/
Masculino
Idioma:
Inglés
Revista:
Int. braz. j. urol
Asunto de la revista:
Urología
Año:
2018
Tipo del documento:
Artículo
País de afiliación:
Brasil
Institución/País de afiliación:
Centro de Oncologia de D'Or/BR
/
Grupo Américas Centro de Oncologia Integrado/BR
/
Hospital Sírio - Libanês/BR
/
Universidade Estadual de Campinas/BR
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