Muerte súbita en epilepsia / Sudden death in epilepsy
Rev. méd. Chile
;
146(8): 902-908, ago. 2018. tab
Artículo
en Español
| LILACS
| ID: biblio-978773
ABSTRACT
The risk of sudden unexpected death in patients with epilepsy (SUDEP), is 20 to 25 times greater than in the general population. This increased risk is seen specially in refractory epilepsy, with an incidence of 91,000 patients-years. Risk factors have been established based on retrospective studies, finding that the frequency of seizures, specially generalized tonic clonic seizures, is the most important one. The physiopathological mechanism of SUDEP is not yet fully understood. Autonomic system abnormalities, as well as cardiac and respiratory changes have been found. The finding of new molecular biomarkers to identify patients with increased risk should be a priority. Treatment is based in the management of risk factors, although clear recommendations are hard to establish given the low level of evidence.
Texto completo:
Disponible
Índice:
LILACS (Américas)
Asunto principal:
Muerte Súbita
/
Epilepsia
Tipo de estudio:
Estudio de etiología
/
Guía de Práctica Clínica
/
Estudio de incidencia
/
Estudio observacional
/
Estudio pronóstico
/
Factores de riesgo
Límite:
Femenino
/
Humanos
País/Región como asunto:
America del Sur
/
Chile
Idioma:
Español
Revista:
Rev. méd. Chile
Asunto de la revista:
Medicina
Año:
2018
Tipo del documento:
Artículo
País de afiliación:
Chile
Institución/País de afiliación:
Clínica Universidad de los Andes/CL
/
Universidad de Los Andes/CL
/
Universidad del Desarrollo/CL
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