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Use of antibiotics by adults: a population-based cross-sectional study
Pereira, Jéssica Quintão; Silva, Marcus Tolentino; Galvão, Taís Freire.
  • Pereira, Jéssica Quintão; Johnson & Johnson Brasil. São José dos Campos. BR
  • Silva, Marcus Tolentino; Universidade Federal do Amazonas. School of Medicine. Manaus. BR
  • Galvão, Taís Freire; Universidade Estadual de Campinas. School of Pharmaceutical Sciences. Campinas. BR
São Paulo med. j ; 136(5): 407-413, Sept.-Oct. 2018. tab
Artículo en Inglés | LILACS | ID: biblio-979384
ABSTRACT
ABSTRACT

BACKGROUND:

The consumption of antibiotics has been widely discussed, mainly because of antibacterial resistance, which has become a worldwide concern. In Brazil, sale of antibiotics is currently ruled by Agência Nacional de Vigilância Sanitária (ANVISA) regulation RDC 20/2011, which restricts sales to those made under medical prescription. The aims of this study were to evaluate antibiotic use and associated factors among adults in the Metropolitan Region of Manaus, Amazonas, Brazil, and to assess the proportion of self-medication from this use. DESIGN AND

SETTING:

Population-based cross-sectional study conducted in the Metropolitan Region of Manaus between May and August 2015.

METHODS:

Adults aged ≥ 18 years were selected through probabilistic sampling in three stages. Trained interviewers collected data from the participants in their homes. Antibiotic consumption over the last 15 days was reported. Bivariate analysis was used to calculate the prevalence ratio (PR) of antibiotic usage, with 95% confidence interval (95% CI). A multivariate model adjusted according to significant variables at P ≤ 0.20 using Poisson regression with robust variance was constructed.

RESULTS:

The prevalence of antibiotic use was 3.4% (95% CI 2.8-4.0%). Adjusted analysis showed that consumption was higher among women than among men (PR 1.58; 95% CI 1.11-2.24) and among people with fair health status than among those with good health (PR 1.52; 95% CI 1.08-2.15). The prevalence of self-medication was 19.0%; amoxicillin was the most self-medicated antibiotic (10/26).

CONCLUSION:

Antibiotic use was associated with women and individuals with fair health status. One fifth of the antibiotics were consumed through self-medication, contrary to the current Brazilian legislation.
Asunto(s)


Texto completo: Disponible Índice: LILACS (Américas) Asunto principal: Automedicación / Antibacterianos Tipo de estudio: Estudio observacional / Estudio de prevalencia / Estudio pronóstico / Factores de riesgo Límite: Adulto / Femenino / Humanos / Masculino País/Región como asunto: America del Sur / Brasil Idioma: Inglés Revista: São Paulo med. j Asunto de la revista: Cirurgia Geral / Ciˆncia / Ginecologia / Medicina / Medicina Interna / Obstetr¡cia / Pediatria / Sa£de Mental / Sa£de P£blica Año: 2018 Tipo del documento: Artículo País de afiliación: Brasil Institución/País de afiliación: Johnson & Johnson Brasil/BR / Universidade Estadual de Campinas/BR / Universidade Federal do Amazonas/BR

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Texto completo: Disponible Índice: LILACS (Américas) Asunto principal: Automedicación / Antibacterianos Tipo de estudio: Estudio observacional / Estudio de prevalencia / Estudio pronóstico / Factores de riesgo Límite: Adulto / Femenino / Humanos / Masculino País/Región como asunto: America del Sur / Brasil Idioma: Inglés Revista: São Paulo med. j Asunto de la revista: Cirurgia Geral / Ciˆncia / Ginecologia / Medicina / Medicina Interna / Obstetr¡cia / Pediatria / Sa£de Mental / Sa£de P£blica Año: 2018 Tipo del documento: Artículo País de afiliación: Brasil Institución/País de afiliación: Johnson & Johnson Brasil/BR / Universidade Estadual de Campinas/BR / Universidade Federal do Amazonas/BR