Clinico-morphological pattern of bone lesions in children

ABSTRACT

The present study was performed to find the spectrum of bone diseases in children and to correlate with age, sex, and site of origin. This was a retrospective study and consists of 95 cases of hone biopsies which were diagnosed in the Department of Pathology at the Institute of Child Health and Children's Hospital, Lahore during a period of six years [Jan 2003-Dec 2008]. These biopsies were evaluated on haematoxylin and eosin stained sections from paraffin embedded tissue blocks. Special stains were performed whenever required. Pyogenic osteomyelitis [OM] accounted for 35.78% of all bone pathologies followed by tuberculous osteomyelitis in 22.10%. Osteosarcoma [OS] was the most frequent [primary tumour of bone followed by Ewing's sarcoma [ES]. One case of metastatic bone tumour was also recorded. Osteochondroma, osteoma, aneurysmal bone cyst, fibro-osseous dysplasia, chondroma and simple bone cyst were also found in children. The bone tumours are relatively more prevalent in males