Local anti-inflammatory and anti-nociceptive activities of coldenia procumbens linn.
Hamdard Medicus. 2007; 50 (1): 76-81
en Inglés
| IMEMR
| ID: emr-102398
ABSTRACT
The ethanolic extract of the leaves of Coldenia procumbens Linn, was studied in Swiss albino mice against 12-O-tetradecanoylphorbol-13-acetate [TPA] and arachidonic acid [AA] induced inflammatory response, while the analgesic effect was studied using the acetic acid-induced writhing in mice and formalin-induced nociception. The ethanolic extract produced dose dependent anti-inflammatory activity against the pathogens. It also showed an inhibitory effect on pain caused by acetic acid in mice and reduced pain episodes induced by formalin. The results indicated that the ethanolic extract produced significant [P<0.05] anti-inflammatory and anti-nociceptive activity when compared with the standard and untreated control
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Índice:
IMEMR (Mediterraneo Oriental)
Asunto principal:
Plantas Medicinales
/
Dimensión del Dolor
/
Acetato de Tetradecanoilforbol
/
Ácido Araquidónico
/
Hojas de la Planta
/
Ácido Acético
/
Formaldehído
/
Ratones
/
Antiinflamatorios
Límite:
Animales
Idioma:
Inglés
Revista:
Hamdard Med.
Año:
2007
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