Efficacy of aloe vera gel in the treatment of vulval lichen planus
JCPSP-Journal of the College of Physicians and Surgeons Pakistan. 2008; 18 (10): 612-614
en Inglés
| IMEMR
| ID: emr-102899
ABSTRACT
To compare the efficacy of aloe vera gel and placebo in the topical management of vulval lichen planus. Randomized, double-blind, placebo-controlled trial. Department of Dermatology, Isra University Hospital, Hyderabad, from January 2007 to January 2008. Thirty-four female patients were randomized into two groups to receive aloe vera gel or placebo for local application for 8 weeks. Clinical data and treatment response was graded according to Thongprasom criteria. Z-test was used for comparing response between the groups. Thirty-four consecutive patients participated in the study. We found erosive and ulcerative lesions in 83% and 17%, respectively. The most common site of vulval lichen planus was the labia minora. Fourteen [82%] out of 17 patients treated with aloe vera had a good response i.e. clinically improved by at least 50% after 8 weeks of treatment, while one [5%] of 17 placebo-treated patients had a similar response [p < 0.001]. Furthermore, one patient [5%] treated with aloe vera had a complete clinical remission. No side-effects were found in both groups. Aloe vera gel was a safe and effective treatment for patients with vulval lichen planus
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Índice:
IMEMR (Mediterraneo Oriental)
Asunto principal:
Enfermedades de la Vulva
/
Método Doble Ciego
/
Administración Tópica
/
Resultado del Tratamiento
/
Manejo de la Enfermedad
/
Aloe
/
Fitoterapia
Tipo de estudio:
Ensayo Clínico Controlado
Límite:
Femenino
/
Humanos
Idioma:
Inglés
Revista:
J. Coll. Physicians Surg. Pak.
Año:
2008
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