[Accuracy of ultrasound in diagnosis of molar pregnancy in patients admitted to Mahdieh hospital 2001-2006]

ABSTRACT

Hydatidiform mole is the commonest type of gestational trophoblastic diseases. Diagnosis of molar pregnancies is essential since molar pregnancies might be associated with maternal complication and would result in malignant trophoblastic disease. Recently, there has been a significant change in clinical presentation of hydatidiform mole due to use of ultrasound in early pregnancy before onset of systemic manifestations. The aim of this study was to assess the accuracy of systemic ultrasound in early diagnosis of molar pregnancies. This was a review of patients with molar pregnancies admitted to Mahdieh hospital from 2001 to 2006. Women with histologically-proven hydatidiform moles were evaluated by their age, gestational age, clinical manifestations and ultrasound findings. All data were analyzed with SPSS. The sensitivity and positive predictive value of ultrasound in diagnosis of hydatidiform mole was calculated. The mean mother's age was 24.84 +/- 6.26 years old. The mean gestational age at the time of evacuation was 12.3 +/- 3.85 weeks. The most common symptom was vaginal bleeding [76.2%]. Basically, there were 49.5% of cases whom were histologically confirmed as complete hydatidiform mole, while 50.5% had partial hydatidiform mole. 81.3% of patients had pre-evacuation sonography compatible with hydatidiform mole. The sensitivity and positive predictive value of ultrasound in detecting the histologically-proved hydatidiform moles were 90% and 100%, respectively. In this study, ultrasound had high accuracy in diagnosis of molar pregnancies. Therefore, sonography is highly recommended in all patients with vaginal bleeding in their first trimester